Hand eczema/dermatitis is a widespread disorder that is often difficult to treat and may be debilitating because of its effects on personal appearance and physical health. Direct costs associated with occupational contact dermatitis in the United States have been estimated at more than $1 billion. Tetrix Cream, the first prescription protectant for these disorders, enhances treatment and prevention with an innova-tive barrier protection cream that is water resistant, long lasting, nongreasy and nonirritating, and also reduces itching and burning.