Injectable poly-L-lactic acid (PLLA) creates new volume by stimulating collagen production. PLLA compensates for age-related changes in tissue shape, with correction enduring for up to 2 years. A defined injection technique is necessary to maximize product efficacy, depending on the area of the face requiring correction. PLLA has a good safety profile, and common device-related adverse events include the formation of delayed, nonvisible, palpable subcutaneous papules. These can be alleviated by using a less concentrated preparation of PLLA, correct placement of PLLA, and postprocedure massage for up to 1 month after injection.